Search results for " tomotherapy"

showing 5 items of 5 documents

Hypo-fractionated stereotactic radiation therapy for lung malignancies by means of helical tomotherapy: report of feasibility by a single-center expe…

2018

Background: Several experiences in the literature report SBRT as an effective treatment option for medically inoperable early stage non-small cell lung cancer (NSCLC) and oligometastatic disease. The optimal fractionation schedules and total dose remain controversial. In this study, we evaluated the safety in terms of toxicity and efficacy of using of 8–10 fractions schedules with Helical Tomotherapy (HT) for primary and metastatic lung lesions. Methods: Between March 2014 and May 2016, a total of 39 patients (median age 72 years, range 26–91) were treated with HT-SBRT for malignant lung lesions: 22 patients with early stage NSCLC, 17 with oligometastases. Patients received 8–10 fract…

AdultMalemedicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentStereotactic radiation therapyRadiosurgerySingle CenterTomotherapy030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineHelical tomotherapyCarcinoma Non-Small-Cell LungmedicineHumansRadiology Nuclear Medicine and imagingStage (cooking)Lung cancerAgedPneumonitisAged 80 and overSBRTHelical tomotherapy; Lung cancer; Radiotherapy; SBRTRadiotherapybusiness.industryRadiotherapy DosageGeneral MedicineMiddle Agedmedicine.diseaseSurvival RateRadiation therapyTreatment Outcome030220 oncology & carcinogenesisFeasibility StudiesFemaleDose Fractionation RadiationRadiologyLung cancerbusinessTomography Spiral ComputedEsophagitis
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Moderate hypofractionated helical tomotherapy for localized prostate cancer: preliminary report of an observational prospective study.

2019

Objective: To report preliminary findings of a phase II study exploring the clinical outcomes of moderate hypofractionated radiotherapy performed with helical tomotherapy (HT) using computed tomography–magnetic resonance imaging–based planning for localized prostate cancer. Methods: The phase II prospective study received ethics approval from our institutional ethics committee. A dose of 60 Gy/20 fractions for low–intermediate risk prostate cancer by means of HT was explored. Primary endpoints of the study were acute and late gastrointestinal (GI) and genitourinary (GU) toxicities. Secondary endpoints were quality of life and biochemical-free survival. Results: A total of 35 patients were i…

Hypofractionated RadiotherapyMaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmenttomotherapyPhases of clinical researchTomotherapy030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancer0302 clinical medicinePreliminary reportProstatemedicineBiomarkers TumorHumansProspective StudiesNeoplasm MetastasisProspective cohort studyRadiometryProstate hypofractionation tomotherapyAgedNeoplasm StagingAged 80 and overhypofractionationbusiness.industryRadiotherapy Planning Computer-AssistedProstateProstatic NeoplasmsGeneral MedicineMiddle Agedmedicine.diseasehypofractionation; Prostate; tomotherapymedicine.anatomical_structureTreatment OutcomeOncology030220 oncology & carcinogenesisQuality of LifeObservational studyRadiation Dose HypofractionationRadiologyRadiotherapy Intensity-ModulatedbusinessFollow-Up StudiesTumori
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[11C]choline-PET-guided helical tomotherapy and estramustine in a patient with pelvic-recurrent prostate cancer: local control and toxicity profile a…

2010

[11C]choline positron emission tomograhy can be useful to detect metastatic disease and to localize isolated lymph node relapse after primary treatment in case of prostate-specific antigen failure. In case of lymph node failure in prostate cancer patients, surgery or radiotherapy can be proposed with a curative intent. Some reports have suggested that radiotherapy could have a role in local control of oligometastatic lymph node disease. This is the first reported case of [11C]choline positron emission tomography-guided helical tomotherapy concomitant with estramustine for the treatment of pelvic-recurrent prostate cancer. At 24 months after the end of helical tomotherapy, prostate-specific…

OncologyMaleCancer Researchmedicine.medical_treatment[11C]choline-PET tomotherapy prostate relapse lymph node030218 nuclear medicine & medical imagingCholineProstate cancer0302 clinical medicineProstateCarbon RadioisotopesTomographyLymph nodeAdjuvantPelvic NeoplasmsrelapseprostateGeneral MedicineAlkylatingmedicine.anatomical_structureTreatment OutcomeLocalOncologyChemotherapy Adjuvant030220 oncology & carcinogenesis[11C]choline-PETEstramustineAged; Antineoplastic Agents Alkylating; Antineoplastic Agents Hormonal; Carbon Radioisotopes; Chemotherapy Adjuvant; Choline; Estramustine; Humans; Male; Neoplasm Recurrence Local; Pelvic Neoplasms; Prostatic Neoplasms; Radiotherapy Adjuvant; Treatment Outcome; Positron-Emission Tomography; Tomography Spiral ComputedEstramustinemedicine.drugmedicine.medical_specialtyAntineoplastic Agents HormonaltomotherapyAntineoplastic AgentsTomotherapy03 medical and health sciencesInternal medicinemedicinelymphChemotherapyHumansAntineoplastic Agents AlkylatingAgedChemotherapyHormonalRadiotherapybusiness.industryProstatic Neoplasmsmedicine.diseaseRadiation therapyNeoplasm RecurrenceConcomitantPositron-Emission TomographySpiral ComputedRadiotherapy AdjuvantNeoplasm Recurrence LocalbusinessTomography Spiral Computed
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END-TO-END TEST IN STEREOTACTIC RADIOSURGERY TREATMENTS THROUGH HELICAL TOMOTHERAPY

2020

STEREOTACTIC RADIOSURGERY HELICAL TOMOTHERAPY
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Dose verification with EPR/alanine dosimeters in Helical Tomotherapy Stereotactic Radiosurgery (HT SRS) treatments

2016

Intracranial stereotactic radiosurgery (SRS) is a technique to deliver an ablative radiation dose with an extremely sharp dose gradient to small brain tumors. This tecnique allows to deliver high doses of radiation to the tumor sparing the surrounding healthy tissue. In this study the accuracy of the dose delivered in a SRS session by a non conventional radiotherapy machine, the TomoTherapy Hi-Art System, was investigated using an "end-to-end" test. This is perfome d by means of alanine Electron Paramagnetic Resonance (EPR) pe llets. The response of these dosimeters is compared to that of gafchromic films which are particularly suitable for two-dimensional dose verification providing accura…

Settore FIS/01 - Fisica SperimentaleSettore MED/36 - Diagnostica Per Immagini E RadioterapiaESR EPR Dosimetry Helical TomotherapyStereotactic Radiosurgery treatmentsSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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